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분화도가 낮을수록 예후가 좋지 않다<ref name=r1 /><ref>Kim KO et al. Clinical overview of extrapulmonary SCC. ''J Korean Med Sci''. 2006 Oct;21(5):833-7. [https://pubmed.ncbi.nlm.nih.gov/17043415/ 연결]</ref><ref>Patel TD et al. Sinonasal NEC : a population-based analysis of incidence and survival. ''Int Forum Allergy Rhinol''. 2015 May;5(5):448-53. [https://pubmed.ncbi.nlm.nih.gov/25727332/ 연결]</ref>. | 분화도가 낮을수록 예후가 좋지 않다<ref name=r1 /><ref>Kim KO et al. Clinical overview of extrapulmonary SCC. ''J Korean Med Sci''. 2006 Oct;21(5):833-7. [https://pubmed.ncbi.nlm.nih.gov/17043415/ 연결]</ref><ref>Patel TD et al. Sinonasal NEC : a population-based analysis of incidence and survival. ''Int Forum Allergy Rhinol''. 2015 May;5(5):448-53. [https://pubmed.ncbi.nlm.nih.gov/25727332/ 연결]</ref>. | ||
== 치료 == | == 치료 == | ||
미국 국립 종합 암 네트워크 (National Comprehensive Cancer Network, NCCN)와 유럽 종양 학회 (European Society for Medical Oncology, ESMO)<ref>Öberg K et al; ESMO Guidelines Working Group. Neuroendocrine bronchial and thymic tumors : ESMO Clinical Practice Guidelines for diagnosis, treatment and FU. ''Ann Oncol''. 2012 Oct;23 Suppl 7:vii120-3. [https://pubmed.ncbi.nlm.nih.gov/22997444/ 연결]</ref> 에서 NEC에 권고되고 있는 고식적 항암제로는 capecitabine, temozolomide, streptozocin, cisplatin, etoposide, doxorubicin, 5-FU 등이 있는데, | 미국 국립 종합 암 네트워크 (National Comprehensive Cancer Network, NCCN)와 유럽 종양 학회 (European Society for Medical Oncology, ESMO)<ref>Öberg K et al; ESMO Guidelines Working Group. Neuroendocrine bronchial and thymic tumors : ESMO Clinical Practice Guidelines for diagnosis, treatment and FU. ''Ann Oncol''. 2012 Oct;23 Suppl 7:vii120-3. [https://pubmed.ncbi.nlm.nih.gov/22997444/ 연결]</ref> 에서 NEC에 권고되고 있는 고식적 항암제로는 capecitabine, temozolomide, streptozocin, cisplatin, etoposide, doxorubicin, 5-FU 등이 있는데, 전이된 고등급의 NEC에서는 cisplatin과 etoposide의 병합 요법이 추천된다<ref>Pavel M et al; Barcelona Consensus Conference participants. ENETS Consensus Guidelines for the management of patients with liver and other distant metastases from neuroendocrine neoplasms of foregut, midgut, hindgut, and unknown primary. ''Neuroendocrinology''. 2012;95(2):157-76. [https://pubmed.ncbi.nlm.nih.gov/22262022/ 연결]</ref>. | ||
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